Professor, Department of Nutrition
Professor, Department of Internal Medicine
Dr. Haj´s laboratory studies the molecular basis of metabolic diseases, mainly obesity and type 2 diabetes. In particular, we are interested in the role of tyrosine phosphorylation and how dysregulation of this key signaling mechanism contributes to metabolic diseases and their complications. We investigate the role of protein-tyrosine phosphatases and their interacting partners in metabolic homeostasis. This is achieved using a combination of genetic, biochemical, proteomic and pharmacological approaches in various experimental platforms (cells, rodent models of disease and humans).